Cardinals take down the 49ers for first time since 2021

For the first time since 2021, the Arizona Cardinals (2-3) beat the San Francisco 49ers (2-3).

With a 24-23 lead, the Cardinals defense stepped up, with Kyzir White picking off Brock Purdy in the final two minutes to seal the victory.

PICKED OFF!!

THE CARDINALS ARE GOING TO TAKE DOWN THE 49ERS ON THE ROAD! pic.twitter.com/xcWDzGKGUx

— FOX Sports: NFL (@NFLonFOX) October 6, 2024

Kyler Murray played solid all day, and broke the internet with a 50 yard touchdown run on the first drive, celebrating from the 44 yard line as he took the top off the defense himself.

Bye bye Ky 👋 @AZCardinals take an early lead!

📺: #AZvsSF on FOX
📱: https://t.co/waVpO909ge pic.twitter.com/EUHKDDLEoO

— NFL (@NFL) October 6, 2024

This team hung around in the game long enough to make plays at the end of the game.

Arizona is now 2-0 in the NFC West after going 0-6 last season.

Next up for Arizona: a trip to Green Bay.